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Figure 2

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Publication: Rostad et al., 2024 - Accelerated Sarcopenia Phenotype in the DJ-1/Park7-Knockout Zebrafish
All Figures: Figures for Rostad et al., 2024

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Figure 2

DJ-1-knockout animals show a high degree of degenerating sub-sarcolemma mitochondria in red muscle. Figure shows transmission electron micrographs of red muscle from 18-month-old wild-type (A) and DJ-1-knockout (B,C) zebrafish. Panel B shows examples of healthy (black asterisk) and degenerating (white asterisk) mitochondria found in red muscle. In wild-type red muscle, mitochondria appeared healthy and no degenerating mitochondria were observed in the sub-sarcolemma (A). In the DJ-1 knockout, a high degree of degenerating mitochondria and autophagic structures (arrows) in the sub-sarcolemma were observed (C).

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Phenotype details

Acknowledgments

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