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Fig. 4 Apigenin mitigates activation of the apoptotic-related pathway. Real-time PCR analysis of the mRNA levels for gadd45ba, serpine1, pmaip1, nfkbiaa, cdkn1a, fosab, gadd45bb, and diabloa in zebrafish larvae treated with cisplatin or apigenin + cisplatin. Results were normalized to GAPDH expression and were presented as mean ± SEM from three independent experiments. CP: cisplatin; API: apigenin ∗∗∗P < 0.001, ∗∗P < 0.01, ∗P < 0.05.
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