ZFIN Image: Kim et al., 2025, Figure 4

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Figure 4

Suppression of angiogenesis and expression of VEGF induced by MP06. (A) Cytotoxicity of H1299 cells and HUVECs treated with MP06. (B) Expression of VEGF in H1299 cells treated with MP06. (C) Tube formation ability of HUVECs in conditioned medium (fresh EBM media/H1299 cultured media with MP06 ratios(75:25, 50:50). (D) Formation of tube-like structures in HUVECs reduced by MP06. Scale bar, 500 μm. ^**P<0.01, ^***P<0.001 vs. control. VEGF, vascular endothelial growth factor; HUVEC, Human Umbilical Vein Endothelial Cells; RT, reverse transcription; WB, western blotting; MP06, Marine peptide 06.

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