ZFIN Image: Kim et al., 2025, Figure 1

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Figure Caption

Figure 1

3D structure of MP06 and cell viability. (A) MP06 contains an N-terminal α-helix and unstructured C-terminal region. Basic amino acids contribute to positive net charge of MP06. (B) Electrostatic potential of MP06. Blue and red regions are the positively and negatively charged regions. (C) Hydrophobic and hydrophilic regions of MP06 are visualized as red and white. (D) FITC-MP06 accumulation was observed in the cytoplasm of H1299 cells. Scale bar, 100 μm. (E) Morphological changes from a spindle shape to a cobblestone-like shape in H1299 cells induced by MP06 and FITC-MP06 peptides. Scale bar, 500 μm. (F) Cell viability. ^**P<0.01, ^***P<0.001; vs. control group. MP06, marine-derived peptide 06; con, control.

Acknowledgments

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