ZFIN Image: Zheng et al., 2024, Figure 8

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Figure Caption

Figure 8

The proposed mechanism underlying the protective effect of the peptide from Nac on hair cells. The peptide reduces the uptake of Gen, protects the mitochondria, improves the endogenous antioxidant system to restrain the excessive accumulation of ROS, and then exerts protective effects against AmAn-induced hair cell damage. The structural characteristics of peptides may contribute to this biological process. Nac, Neptunea arthritica cumingii; Gen, gentamicin; ROS, reactive oxygen species; AmAn, aminoglycoside antibiotics.

Acknowledgments

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