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Fig. 2 Abnormality of head structure in the paqr5b?/? mutant. (A) Survival rates of adult paqr5b+/+ and paqr5b?/? mutant fish (F6 generation). The number of surviving adult paqr5b+/+ and paqr5b-/- fish (left panel) and the percentage of head abnormalities (right panel) in each of the three batches were compared. Each value represents the mean of the data, and the vertical lines indicate the standard deviations. Asterisks represent significant differences between paqr5b+/+ and paqr5b?/? fish (* P ? 0.01). (B) Representative morphologies of the head region of adult paqr5b+/+ and paqr5b?/? fish are shown. The scale bars in the upper panels are 1 cm. The scale bars in the lower panels are 1 mm. (C) Micro-CT scan of the head skeleton of paqr5b+/+ and paqr5b?/?. The upper panels are volume-rendered images, and the lower panels are maximum-intensity projection images. Scale bars are 1 mm.