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Fig. 4 Anti-TNF nonresponders have lower levels of TNF methylation than responders. (A and B) TNF methylation analysis of anti-TNF responders and nonresponders in uninflamed (A) or inflamed (B) mucosa (responders, uninflamed, n = 18 samples; nonresponders, uninflamed, n = 14 samples; responders, inflamed, n = 8 samples; nonresponders, inflamed, n = 12 samples). Data points are average methylation values from individual cases. Mean ± SD are plotted. P values were calculated using parametric unpaired t-tests. SD, standard deviation; TNF, tumor necrosis factor.
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