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Fig. 1 Experimental design and timeline of the study. Fish were divided into the four experimental groups of control, Dextrose, CUMS, and CUMS + Dextrose. The Dextrose and CUMS groups were exposed to 111 mM dextrose solution and the CUMS procedure, respectively, for 14 days. At the end of the 14-day treatment, fasting blood glucose levels and body weights were measured, followed by whole brain sample extraction for downstream experiments. CUMS, chronic unpredictable mild stress.
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