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Fig. 6 Improvement in saccadic amplitude in Joubert syndrome patient upon nicotinamide supplementation. (A) Schematic of eye tracking design. (B) Joubert syndrome patient undergoing examination. (C) Representative image of target, fixation point, and eye positions for eye tracking exam. (D) Saccadic amplitude and SEM for the last 2 sessions (101 trials) before and on treatment with nicotinamide (oral 250 mg daily for 2 months) (8,707 saccades, before-treatment group, vs. 3,359 saccades, on-treatment group). Exact P values are indicated. One-tailed Student’s t test.
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Full text @ Journal of Clin. Invest.