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Figure Caption
Fig. 6 Ambra1 knockout affects heart development also in mouse. Statistical analysis of the penetrance of heart phenotype in Ambra1gt/gt embryos of different genetic strains (A). Hematoxylin/eosin staining on sections of E13.5 embryos (B). Ambra1gt/gt embryos display thinner walls of cardiac muscle (short arrows) and no difference in thickness of the trabecular layer (long arrows). At this stage, mouse embryos displayed disorganization of the ventricular trabeculae. Scale bar, 200 μm. Color images are available online.
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