Fig. 5

Fig. 5

Behaviour of WT and heterozygous sa17298 zebrafish larvae at 6 dpf in the light-dark transition test. Each dot represents an individual larval measurement. Data analysed using non-RM two-way ANOVA followed by Tukey’s post hoc test. Data represented as mean ± SD. a Light-dark transition elicits an increase in locomotor activity in both genotypes with locomotor difference between cacna1da^WT/WT and cacna1da^sa17298/WT reaching statistical significance in both illumination states. * (p < 0.05), ** (p < 0.01): [cacna1da^WT/WT vs cacna1da^sa17298/WT] in the dark, #### (p < 0.0001): [cacna1da^WT/WT vs cacna1da^WT/WT] and [cacna1da^sa17298/WT vs cacna1da^sa17298/WT]. b Zone preference of WT and heterozygous sa17298 larvae (thigmotaxis) represented as % total distance moved in the outer zone in the light-dark transition test