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Figure 3.

ID: ZDB-IMAGE-240612-5
Publication: Rahmati et al., 2024 - Fine-tuning amyloid precursor protein expression through nonsense mediated mRNA decay
All Figures: Figures for Rahmati et al., 2024

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Figure 3.

Expression of app family genes in embryos injected with unstable or stable appb^−/− mRNA. A, Injection of capped appb^−/− RNA increases mRNA levels of appb but not mRNA level of appa, aplp1, or aplp2 compared with control eGFP RNA (N = 10–14). B, Injection of uncapped appb^−/− RNA increases mRNA levels of appb and appa, compared with uncapped control eGFP RNA (N = 8–15). A, Bn = 3 biologically independent samples. Student's two-tailed t test was used to calculate p values. Wild-type expression levels were set to 1. Data shown as mean + SD. **p < 0.01 and ****p < 0.0001. ns, nonsignificant.

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