IMAGE

Figure 9.

ID: ZDB-IMAGE-240612-10
Publication: Rahmati et al., 2024 - Fine-tuning amyloid precursor protein expression through nonsense mediated mRNA decay
All Figures: Figures for Rahmati et al., 2024

Image

Figure Caption

Figure 9.

TA in hNPCs but not in terminally differentiated neuron cells transfected with unstable hAPP695 mRNA. A, Relative APP level in hNPCs transfected with uncapped eGFP (control) or hAPP695 mRNA (N = 9). B, APLP1 and APLP2 levels in hNPCs transfected with uncapped eGFP (control) or hAPP695 mRNA (N = 9). C, Relative APP level in human neuron cells transfected with uncapped eGFP or hAPP695 mRNA (N = 9). D, Relative mRNA level of APLP1 and APLP2 in terminally differentiated neuron cells transfected with uncapped eGFP or hAPP695 mRNA (N = 13). APP in control eGFP transfected cells were set at 1. A–D, n = 3 biologically independent samples. Data are mean + SD. Student's t test was used to calculate p values. *p < 0.05, **p < 0.01, ***p < 0.005, and ****p < 0.0001. ns, nonsignificant.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ eNeuro