ZFIN Image: Zhu et al., 2024, Figure 5

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Figure 5

Comparison of changes in biological functions and pathways between the kras+ zebrafish liver and the PH liver. (A) Comparison between the changes in the activity of Hallmark gene sets in the kras+ liver on Day 5 following Dox induction and those in the PH livers on Day 1 following PH based on the GESA of Hallmark gene sets. The color key indicates the direction of changes (red: upregulation; green: downregulation) and significance (adjusted p-value). (B,C) GESA of KEGG pathway in (B) kras+ livers on Day 5 following Dox induction and (C) PH livers on Day 1 following PH. The size of the dots indicates the number of leading-edge genes in the corresponding gene set. The color key indicates significance in adjusted p-value. Gene Ratio is the ratio of leading-edge genes versus all genes in the gene set.

Acknowledgments

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