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Fig. 3 E2 supplementation promotes sex-specific changes in liver lipid metabolism. Female (top) and male (bottom) hepatic qPCR analysis after an overnight fast. Hepatic expression of (A, D) fasn, (B, E) hmgcr, and (C, F) ldlr normalized to ?-actin. Tissues were analyzed after 6 weeks of experimental diet. Error bars indicate mean ± SEM, n = 3?5 for females and n = 3?6 for males. Statistical tables for these data are provided in Supplementary Figures 10 and 15. *p < 0.05.
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