Fig 1

Fig 1

A) A custom-made hypergravity centrifuge was used to perform the experiments. B) Gondola with the 96 well plate where the larvae were placed during the 5 days of treatment. C) Graphical representation of the centrifuge and gondola showing the variables and vectors used to calculate the value of the acceleration (artificial hypergravity) at the center of the gondola. The centrifuge radius, R, is defined as the distance from the center of rotation to the outer edge of the platter. The gondola arm length l was measured from the outer edge of the platter of the centrifuge to the end of the gondola. Both of them (R and l) were measured with a tape measure. The angle, θ, was calculated using taking an image and analyzing it using a program called Angulus (DPP v1 2020). r is the gondola radius, ν is the tangential velocity due to rotation, ac is the centripetal acceleration, and ω is the angular velocity.