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Fig. 4

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Publication: Raote et al., 2024 - TANGO1 inhibitors reduce collagen secretion and limit tissue scarring
All Figures: Figures for Raote et al., 2024

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Fig. 4 Effects of peptide treatment on the secretome of human fibroblasts.

A Volcano plot illustrating significantly downregulated (blue symbols) and upregulated (orange symbols) proteins, by treatment of primary human dermal fibroblasts with 40 μM P2 + P5 for 20 h in serum-free conditions in comparison to control samples. Unpaired two-sided Student´s t-test, S₀ = 0.1, N = 3 independent samples. B Gene ontology (GO) terms of proteins affected by peptide treatment. Box plot represents the median, 25^th and 75^th percentiles, max. and min. are connected through whiskers. Outliers are defined as Q₁−1.8 interquartile range (IQR) and Q₃ + 1.8 IQR. An unpaired two-sided Student´s test was performed.

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