ZFIN Image: Rayner et al., 2024, Fig. 5

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Figure Caption

Fig. 5 Mutant cyclin F can deplete TDP-43. A. Flow cytometry evaluation of effect of cyclin FWT, cyclin FMRL/AAA or mCherry on TDP-43-GFP MFI. B. Western blot evaluation of effect of cyclin FWT, cyclin FMRL/AAA or mCherry on TDP-43 abundance. C. Densitometry analysis of immunoblots shown in B. D. Flow cytometry evaluation of effect of cyclin FWT, cyclin FMRL/AAA or mCherry on TDP-43ΔNLS-GFP MFI. E. Western blot evaluation of effect of cyclin FWT, cyclin FMRL/AAA or mCherry on TDP-43ΔNLS-GFP MFI. F. Densitometry analysis of immunoblots shown in E. For all data, graphs represent the mean and SD. N = 3. *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001, ****p ≤ 0.0001.

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