IMAGE

Fig. 2.

ID: ZDB-IMAGE-240412-44
Publication: Carey et al., 2024 - Distinct features of the regenerating heart uncovered through comparative single-cell profiling
All Figures: Figures for Carey et al., 2024

Image

Figure Caption

Fig. 2.

Medaka lack an endogenous injury-induced interferon response. (A) Gene expression heatmap showing scaled average gene expression for 12 interferon-stimulated genes in the indicated species and tissue type at each time point. (B) RNA in situ hybridization of isg15 (interferon-responding cells), kdrl (endothelial cells), and myl7 (cardiomyocytes) in ventricle cryosections in the indicated species and time point. Scale bars: 200 µm. Anatomical labels: V, intact ventricle; BA, bulbus arteriosus; W, wound area. Images are representative of at least three individuals at each time point. (C) Gene expression feature plot for ifnphi1 across all zebrafish cardiac cell types, color scale=expression level. (D) Quantification of proportion of zebrafish endothelial cells expressing ifnphi1 at each time point.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Biol. Open