ZFIN Image: Liang et al., 2024, Fig. 6

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Fig. 6

Csrp3 deficiency impairs injury-induced CM dedifferentiation and sarcomere reassembly. A Immunostaining of cTnT indicated that sarcomere disassembly of 218A CMs was not blocked but instead exacerbated during regeneration while sarcomere reassembly was hindered. Scale bars, 20 μm. B WISH showed reduced expression of cardiogenic factors nkx2.5 and hand2 in ablated 218A larval hearts during regeneration. Scale bars, 50 μm. C Immunostaining showed reduced embryonic Myh7 signal in the border zone of injured 218A adult ventricle at 7 dpci. Scale bars, 100 μm

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