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Fig. 5 Reproductive success. Estimated fecundity (A, B, number of eggs per tank) and 24 h survivorships of offspring eggs (C, D, percent) of DNMT3a+/+ (A, C) and DNMT3a−/− (B, D) genotypes exposed to BPA (filled circles = control; open circles = BPA exposure) at different temperatures (blue symbols = 24 °C, red symbols = 30 °C). Fecundity was influenced by an interaction between BPA exposure and treatment, decreasing fecundity at 30 °C, and survival was determined by a three-way interaction between genotype × temperature × BPA exposure. Note that parents were exposed directly to BPA but offspring were reared in clean water. Means ± s.e. are shown from 9 to 17 tanks per treatment.