ZFIN Image: Altbürger et al., 2023, Fig. 3

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Figure Caption

Fig. 3 Absence of Ascl1 activity leads to a significant decrease of dopaminergic neurons. (A–I) Cell counts (DAC4 data not shown) and (J) statistical analysis of the immunofluorescence staining shown in Fig. S1. Neuron numbers of different genotypes were compared using the Wilcoxon-Mann-Whitney rank-sum non-parametric test. P-values indicate significance if they are <0.05 (**, 0.001–0.01; ***, 0.0001–0.001). For numbers of analyzed embryos see Supplemental Table S2. Abbreviations: DAC, dopaminergic cluster; Hyp, hypothalamus; ns, not significant; OB, olfactory bulb; Po, preoptic region; Pr, pretectum; Pth, prethalamus; Sp, subpallium.

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Reprinted from Developmental Biology, 505, Altbürger, C., Rath, M., Wehrle, J., Driever, W., The proneural factors Ascl1a and Ascl1b contribute to the terminal differentiation of dopaminergic GABAergic dual transmitter neurons in zebrafish, 587458-74, Copyright (2023) with permission from Elsevier. Full text @ Dev. Biol.