IMAGE

Fig. 6

ID

ZDB-IMAGE-240212-34

Genes

Publication

Kim et al., 2024 - Impairments of cerebellar structure and function in a zebrafish KO of neuropsychiatric risk gene znf536

All Figures

Figures for Kim et al., 2024

Image

Figure Caption

Fig. 6 Defects in cerebellar structure and function in znf536 KO zebrafish.

A, B”’ Reduced neuronal activity in KO zebrafish monitored by c-fos expression after novel tank assay, especially in the cerebellum (arrowheads). n = 3 for WT and n = 3 for KO. C Expression of Purkinje cell markers (aldoca, pvalb7, ca8) were specifically affected in the Va region. n = 3 for WT and n = 3 for KO for each marker. D Confocal images of myelinated bundles in Tg[mbp:mgfp]::znf536 KO brain, focused in the Va region. A unique circular structure (asterisk) was identified within the Va. n = 2 for WT and n = 2 for KO. CCe corpus cerebelli, Dm medial zone of the dorsal telencephalic area, TeO optic tectum, Va valvular cerebelli. Scale bars: 500 µm.

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Transl Psychiatry