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Fig. 8

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ZDB-IMAGE-240131-55
Source
Figures for Li et al., 2024
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Figure Caption

Fig. 8 The working model showing zebrafish Cebps in balancing granulopoiesis.

HSC or myeloid progenitor (MP) undergo stepwised differentiation for granulopoiesis. The neutrophil lineage cells contain proNeu1, proNeu2, pre.Neu, and mat.Neu, which nomenclature is based on a previous study39. The eosinophil lineage cells contain Eb-P, EoP, pre.Eos, and mat.Eos. For granulopoiesis, Cebp1 is essential for the generation of the neutrophil lineage, and Cebp1 suppresses Cebpβ to inhibit the commitment and differentiation of the eosinophil lineage.

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