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Publication: Sun et al., 2024 - amer1 Regulates Zebrafish Craniofacial Development by Interacting with the Wnt/β-Catenin Pathway
All Figures: Figures for Sun et al., 2024

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Figure 1

Identification of AMER1 and its homologous gene in zebrafish. (A) Schematic diagram of AMER1 sequences in families of patients with dichotomous monozygotic twins with microtia. The AMER1 variant (c.61C>T: p.R21C) was detected in two patients with sporadic microtia (shaded), as well as in their normal twins and parents (blank). The predicted protein structure showed dramatic changes from wildtype, and pathway prediction showed a relationship between AMER1 and the Wnt pathway. (B) BLAST analysis of sequences homologous to human AMER1 in zebrafish. (C) Expression profile of zebrafish amer1, as determined using the Spatial Transcript Omics DataBase.

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