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Fig. 8 Estradiol treatment after brain injury reduces blood–brain barrier (BBB) leakage. Zebrafish males treated with 10−7 M of E2 after telencephalic injury show a significant decrease in Evans blue extravasation and consequently a decreased BBB leakage 1 day after the lesion compared to untreated fish. n = 6-7 brains (six controls and seven treated with estradiol). *p < .05.
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Full text @ J. Comp. Neurol.