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Figure 6

ID: ZDB-IMAGE-240113-37
Publication: Sobah et al., 2023 - Contribution of Signal Transducer and Activator of Transcription 3 (STAT3) to Bone Development and Repair
All Figures: Figures for Sobah et al., 2023

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Figure 6

Effect of Stat3 mutations on fin regeneration. Representative images of wildtype (WT: A), knockout (KO: B), and transactivation domain truncation (ΔTAD: C) zebrafish subjected to staining with calcein and Alizarin red at the indicated timepoints, showing staining with each separately and then overlaid (Merge), with scale bars representing 1 mm. Quantification of caudal fin regeneration as the length from the amputation site to the newly formed fin ray tip (D) showing mean with SEM and statistical significance indicated (*** p < 0.001). Relative survival following amputation (E), presented as a Kaplan–Meier plot with statistical significance indicated between WT and KO (*** p < 0.001) as well as WT and ΔTAD (### p < 0.001).

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