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Figure S5.

ID: ZDB-IMAGE-240111-31
Publication: Heins-Marroquin et al., 2024 - CLN3 deficiency leads to neurological and metabolic perturbations during early development
All Figures: Figures for Heins-Marroquin et al., 2024

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Figure Caption

Figure S5. Untargeted metabolomics analysis using LC-MS (experiment 1).

(A) Principal component analysis for WT (black) and MUT1 (blue) zebrafish larvae based on all variables (m/z features) detected in positive and negative modes. The first principal component (PC1) explains 25.7% of the variation, the second component 14.9%, and the third component 10.3%. (B) Violin plots showing normalized abundance values for the indicated acylcarnitines in WT and MUT1 samples. Statistically significant differences between lines were determined using an unpaired multiple Welch’s t test (*P ≤ 0.05; **P ≤ 0.01; ***P ≤ 0.001; and ****P < 0.0001).

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