ZFIN Image: Belmonte-Mateos et al., 2023, FIGURE 6

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Figure Caption

FIGURE 6

Progenitor cells in the rhombomere centers are Notch-responsive. Wild-type embryos were treated with either DMSO (A–E, K–L) or the gamma-secretase inhibitor LY411575 (F–J, M,N) for 6 h at 36 hpf (A–J) or at 48 hpf (K–N). Embryos were in situ hybridized with fabp7a(A,F,K,M), slc1a2a(B,G), neuroD4(C,H), and hey1(E,J), or immunostained with Sox2 and HuC (D,I,L,N). Dorsal MIP with anterior to the top. White arrowheads indicate the rhombomere boundaries. Numbers at the bottom indicate the individuals with the displayed phenotype over the total of analyzed specimens. Scale bar, 50 μm.

Acknowledgments

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