ZFIN Image: Schleser et al., 2023, Fig. 5

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Figure Caption

Fig. 5 Confocal imaging of 518A2 melanoma cells treated with 25 μm of cyclopropene derivatives 20 or 21 and BDP-FL-tetrazine for bioorthogonal labelling (green), or with MitoTracker® Red CM-H2XRos (violet), or DAPI (blue). Images are representative of at least two independent experiments. Scale bars correspond to 50 μm, magnification 640×. Pearson correlation coefficient (PCC) was calculated for colocalised nuclei and mitochondria using the coloc2 function (image J). The bottom scheme shows the general cycloaddition reaction of cyclopropenes 20 and 21 with BPD-FL-tetrazine to give fluorescent diazines.

Acknowledgments

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