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Fig. 2 Co-treatment with MM-201 protects utricular hair cells from gentamicin exposure in vitro. (A-C) Representative extrastriolar images of (A) untreated, (B) 5 mM gentamicin, or (C) 5 mM gentamicin plus 1 pM MM-201 treated utricles. (D) 1 pM MM-201 robustly protects utricular explant hair cells from gentamicin exposure (One-way ANOVA: F3,7 = 19.38 p = 0.0009). Asterisks indicate significant difference from gentamicin-exposed group (**p<0.01). N = 2–4 utricular explants per treatment, error bars represent + s.d.
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Reprinted from Hearing Research, 434, Uribe, P.M., Hudson, A.M., Lockard, G., Jiang, M., Harding, J., Steyger, P.S., Coffin, A.B., Hepatocyte growth factor mimetic confers protection from aminoglycoside-induced hair cell death in vitro, 108786108786, Copyright (2023) with permission from Elsevier. Full text @ Hear. Res.