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Figure 2

ID: ZDB-IMAGE-231002-21
Publication: van Alen et al., 2023 - Mycobacterium tuberculosis β-lactamase variant reduces sensitivity to ampicillin/avibactam in a zebrafish-Mycobacterium marinum model of tuberculosis
All Figures: Figures for van Alen et al., 2023

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Figure 2

Activity of Mtb BlaC mutants produced in Mmar. Cultures of Mmar chromosomally expressing wild-type BlaC or variants S70A (negative control), I105F, G132N, G132S, D172N, D179N, and K234R were incubated for 8 days at 30 °C on plates containing 20 or 80 μg mL⁻¹ ampicillin, or 8 μg mL⁻¹ sulbactam or 12 μg mL⁻¹ avibactam in the presence of 15 μg mL⁻¹ ampicillin. The complete plates are shown in Figs. S2–S4.

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