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Publication: Elsaid et al., 2023 - Proteomic analysis unveils Gb3-independent alterations and mitochondrial dysfunction in a gla^-/- zebrafish model of Fabry disease
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Fig. 1

Proteomic comparison of kidneys from wild-type (WT; n = 8) and mutant (MU; n = 8) zebrafish. Gene ontology (GO) enrichment analysis and KEGG analysis. A Hierarchical clustering for differentially expressed proteins between WT and MT. Downregulated proteins in MU compared to WT in B GO Biological Process analysis; C GO Cellular component analysis; D GO Molecular function analysis. Upregulated proteins in MU compared with WT in E GO Biological Process analysis; F GO Cellular component analysis; G GO Molecular function analysis. H KEGG pathways related to downregulated proteins in MU compared to WT. I KEGG terms associated with upregulated proteins in MU vs. WT. Enrichments are reported as false discovery rates (FDR) ≤ 0.05. The twenty most enriched pathways are represented

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