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FIGURE 4

ID: ZDB-IMAGE-230916-22
Publication: DeMoya et al., 2023 - Sin3a associated protein 130 kDa, sap130, plays an evolutionary conserved role in zebrafish heart development
All Figures: Figures for DeMoya et al., 2023

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FIGURE 4

RNAseq reveals cardiac contraction and conduction is altered in MZsap130a(A) Representative images of Tg(myl7:EGFP) and MZsap130a;Tg(myl7:EGFP) embryos collected for whole embryo RNAseq at 36hpf. (B) Volcano plot of 36hpf whole embryo RNAseq data. (C) Heatmap of sarcomere and conduction genes (Supplementary Figure S6) at 36hpf from whole embryos. (D) DAVID functional annotation cluster 8 from downregulated genes in MZsap130a, showing DAVID calculated p-values. (E) Heatmap of 48hpf heart tissue RNAseq data for the same genes found in panel C. V and A are ventricle and atria, respectively. Scale bar 100 μm.

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