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Fig. 1
Regional association plots of BAV risk loci on chromosome 1p21 near PALMD (A), 8p23 near GATA4 (B) and 3q29 within MUC4 (C). At each locus, associations [−log10(P-values)] are shown for SNPs flanking 400 kb on either side of the lead associated SNP. The lead variant is indicated by the corresponding rs-number. Other markers at each locus are displayed by different colours, which indicate different levels of LD (r2) to the lead SNP. Furthermore, all annotated genes within each region are shown with arrows indicating their transcription direction.
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