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Figure 5

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Publication: Nieoczym et al., 2023 - In Silico Analysis, Anticonvulsant Activity, and Toxicity Evaluation of Schisandrin B in Zebrafish Larvae and Mice
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Figure 5

The effect of schisandrin B on hatching at 72 and 96 hpf (A); swim bladder inflation (B); yolk sac abnormalities (C); heart malformation (D); hemorrhage (E) and body shape of 96 hpf old larvae (F). Zebrafish larvae were exposed to schisandrin B at a concentration range of 0.375–6 µM for 95 h. All scores were performed in triplicates and the results were pooled together. The experimental groups consisted of the following number of zebrafish larvae: vehicle + vehicle − 36, schisandrin B 0.375 µM − 32, schisandrin B 0.75 µM − 33, schisandrin B 1.5 µM − 36, schisandrin B 3 µM − 36, schisandrin B 6 µM − 34. * p < 0.05; ** p < 0.01; *** p < 0.001 vs. control group, Fisher’s exact test.

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