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Figure 4

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Publication: Nieoczym et al., 2023 - In Silico Analysis, Anticonvulsant Activity, and Toxicity Evaluation of Schisandrin B in Zebrafish Larvae and Mice
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Figure 4

The effect of schisandrin B on c-fos (A) and bdnf (B) mRNA expressions in PTZ-bathed larval zebrafish. Six-day-old fish were incubated with schisandrin B (3 µM) for 24 h and subsequently exposed to PTZ (20 mM). After a 90 min delay, fish were collected and pooled (10/sample). Data were analyzed using one-way ANOVA with the Tukey’s post hoc test. Data are depicted as individual measurements (as symbols) and mean + SEM (n = 8/group). *** p < 0.001 vs. vehicle + vehicle; ^{^^^}p < 0.001, ^{^^} p < 0.01 vs. vehicle + PTZ. PTZ − pentylenetetrazole.

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