ZFIN Image: Yang et al., 2023, Figure 3

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Figure 3

Knock out of cdh23 resulted in impaired hair cell function. The function of hair cells is evaluated by performing a YO-PRO-1 uptake experiment at 6 dpf. The ear hair cell (A) and lateral neuromast (B) uptake YO-PRO-1, while in the cdh23 homozygous mutant, the ear hair cell (C) and lateral neuromast (D) (arrow) do not have YO-PRO-1 fluorescence signal. (E) Genotyping results confirmed that the embryos with impaired function of hair cells are homozygous mutants. (F) The numbers of hair cells in each group, ***, significant difference, p<0.001.

Acknowledgments

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