ZFIN Image: Jami et al., 2021, Fig. 5

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Figure Caption

Fig. 5

Cyp1A knockdown model. A Lack of induced expression of Cyp1A confirmed the KD efficiency; the expression levels were normalized to Elf-alpha as an internal control. Additionally, from the RNA-seq results table, the succinate dehydrogenase complex subunits B (SDHB) with stable expression between groups was selected as a secondary internal control. B The KD embryos had decreased survival in both treated and control conditions, but there was a significantly increased vulnerability to DEPe in KD embryos compared to controls. C Increased rate of morphological defects in KD embryos after exposure to DEPe demonstrates increased vulnerability in the absence of Cyp1A. The asterisks indicate statistical significance (∗ ∗ = p < 0.01, ∗ = p < 0.05)

Acknowledgments

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