ZFIN Image: Wang et al., 2023, Figure 3

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Figure Caption

Figure 3

Knockdown of the ndrg2 gene induced weakened response behavior to sound stimuli in zebrafish (Danio rerio) at 5 dpf. (A) Schematic diagram of the devices used in startle response assay and sound vibration stimuli modes applied to larvae. (B) Extracted locomotion trajectories from larvae with C-shape motion under one-time stimulus of 9 dB re.1 ms⁻² sound level with 180 Hz tone bursts in control, ndrg2 morphants, and ndrg2 mRNA rescued groups, respectively. (C,D) Statistical analysis of the mean distance and peak velocity of locomotion under two levels stimuli in normal, ndrg2 morphants, and ndrg2 mRNA rescued larvae at 5 dpf, respectively (n = 20). Symbols of *, **, ***, and **** above bars represent p < 0.05, p < 0.01, p < 0.001, and p < 0.0001, respectively. ns, no significance.

Acknowledgments

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