IMAGE

Figure 4

ID: ZDB-IMAGE-230629-7
Publication: Tang et al., 2023 - Tg(Δ113p53:cmyc) Transgene Upregulates glut1 Expression to Promote Zebrafish Heart Regeneration
All Figures: Figures for Tang et al., 2023

Image

Figure Caption

Figure 4

cMyc is conditionally overexpressed in ∆113p53⁺ CMs in Tg(∆113p53:cmyc) zebrafish hearts. (A) Immunostaining of MF20 (in red), GFP (in green) and cMyc (in white) in Tg(∆113p53:GFP) single and Tg(Δ113p53:cmyc);(TgΔ113p53:GFP) double transgenic zebrafish hearts at 14 dpa. Scale bar: 20 μm. n: 11–12 hearts/sample. (B,C) Representative pictures of WT and Tg(∆113p53:cmyc) adult zebrafish hearts (B). The statistical analysis of the average ventricle sizes of Tg(∆113p53:cmyc) and WT adult zebrafish is shown in (C). Each dot represents an individual heart (round dot, WT group; frame dot, Tg(∆113p53:cmyc) group). n: 11–12 hearts/sample. Statistical analysis was performed by Student’s two-tailed unpaired t test in GraphPad Prism 8. The p values were represented by n.s. and asterisks. n.s., p > 0.05.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J Cardiovasc Dev Dis