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Fig. 3
HF phenotype induced by TER in the DM zebrafish model. (A) Representative fluorescent microscopic images of the Tg (myl7:EGFP) zebrafish heart with a GFP at 7 dpf. (B) vFS (n = 21–26 per group). (C) Representative blood pulse graphs. (D) SD of the beat-to-beat interval (n = 21–28 per group). (E) Relative mRNA expression of nppb (n = 8 per group). Each group had 8 samples, with 10 larvae per sample. Data are presented as mean ± SD and each dot represents the value of each sample.
DM = diabetes mellitus; dpf = days post-fertilization; EGFP = enhanced green fluorescent protein; HF = heart failure; myl7 = myosin light chain 7; SD = standard deviation; TER = terfenadine; Tg = transgenic; VD = ventricular diastole; VEH = vehicle; VS = ventricular systole.
*p<0.05, **p<0.01, ****p<0.0001 vs. indicated group.
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Full text @ Korean Circ J