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Figure 5
Swimming exercise restores mitophagy in diet-induced NAFLD model zebrafish livers. (A) Representative TEM of zebrafish liver. (B) Western-blot of PINK1, PARKIN, and p62 (n=6). Protein expression levels of (C) PINK1, (D) PARKIN, and (E) p62 according to densitometry. * p < 0.05, ** p < 0.01, *** p < 0.001. Data represent the mean, and error bars represent SEM. Scale bar on TEM 20000× micrograph, 1 μm. The red arrows indicated the mitophagosomes. NAFLD, non-alcoholic fatty liver disease; N, normal diet; H, high fat diet; HE, high-fat diet plus exercise. ns, not significant.
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