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Figure 1
Protective effect of swimming exercise against diet-induced NAFLD in zebrafish. (A) Schematic of the swimming exercise strategy to study diet-induced NAFLD in zebrafish. (B) Body length, (C) body weight, and (D) body mass index of zebrafish during the experimental period. (E) HE staining, MASSON staining, and DHE visualization of zebrafish liver tissue in response to a high-fat diet and a high-fat diet combined with exercise (n=3). (F) NAS score, (G) fibrosis score, and (H) DHE integrated density in zebrafish livers. *, p < 0.05, **, p < 0.01, ***, p < 0.001. Data represent the mean, and error bars represent the SEM. Scale bar, 20 μm. NAFLD, non-alcoholic fatty liver disease; N, normal diet; H, high fat diet; HE, high-fat diet plus exercise. ns, not significant.