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Publication: Grabinski et al., 2023 - Comparative analysis of transcriptional changes in zebrafish cep290 and bbs2 mutants by RNA-seq reveals upregulation of inflammatory and stress-related pathways
All Figures: Figures for Grabinski et al., 2023

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Figure 2

Enrichment of differentially expressed genes in biological processes of interest in cep290 and bbs2 mutants. (A) Log/log plot of DEG fold changes of common DEGs in cep290^−/− and bbs2^−/− datasets. Blue circles represent downregulated DEGs. Red circles represent common upregulated DEGs. Purple circles are DEGs upregulated in bbs2^−/− retina but downregulated in cep290^−/− retinas. Green circles are DEGs downregulated in bbs2^−/− retinas but upregulated in cep290^−/− retinas. (B) Heat map of the log₂ fold change in the top 50 most abundantly expressed of the 815 DEGs in common by read count. Most DEGs were downregulated. (C) Heat map of the log₂ fold change in the top 50 DEGs with greatest fold change in expression.

Acknowledgments

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