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Fig. 1
Protein alignment of INPP5K, Inpp5ka, and Inpp5kb highlighting conserved amino acids required for phosphatase activity. The start and end of the catalytic domain in the human protein are marked with large red arrowheads. Amino acids required for phosphatase activity have been denoted with asterisks (*). Small arrowheads indicate residues that are altered by missense variants in humans. Hs,
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