ZFIN Image: Yang et al., 2022, Fig. S2

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Figure Caption

Fig. S2 Additional features of positional homeostasis, related to Figure 1

(A) Trajectories of an example fish swimming against different flow velocities in the swim period.

(B and C) Behavior when flow velocity in the swim period is lower or higher than that in the pre-displacement period.

(D) Swimming in the pre-displacement or delay periods does not influence eventual fish location, i.e., fish track the visual stimulus and use integrated visual flow.

(E) Stimuli used to test if visual flow is sufficient for positional homeostasis. The periodic pattern looks the same when translated by an integer number of finely spaced periods. During the pre-displacement period, the fish transitions an integer number of periods. In the delay period, the screen becomes blank to additionally test whether animals are locking on to a specific feature of their environment. In the swim period, the pattern becomes visible again. Single-fish and population data shows convergence, i.e., positional homeostasis can be based only on integrated visual flow.

Acknowledgments

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Reprinted from Cell, 185, Yang, E., Zwart, M.F., James, B., Rubinov, M., Wei, Z., Narayan, S., Vladimirov, N., Mensh, B.D., Fitzgerald, J.E., Ahrens, M.B., A brainstem integrator for self-location memory and positional homeostasis in zebrafish, 50115027.e205011-5027.e20, Copyright (2022) with permission from Elsevier. Full text @ Cell