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Fig. 8 MO-mediated knockdown of the components of the nphp1-4-8 module. TBMs were used to deplete zebrafish nphp1, nphp4 and nphp8 as indicated. Glomerular cysts and cloaca malformation (cloaca cysts) were expressed in comparison with control MO-injected zebrafish embryos. The control represents the average of six independent control MO injections at concentrations between 0.2 and 0.4 mm. The MO concentrations (mm) are shown below the group names.
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