Figure 4.

(A) Schematic view of the mean-field Ising model. (B) Examples of simulated mL and mR signals of the mean-field dynamical equations for two sets of parameters that correspond to fish ID #5 at two water temperatures (22°C and 30°C), see Appendix 2—table 2. (C) Free-energy landscapes in the (mL,mR) plane computed with the mean-field model. These data correspond to the same sets of parameters as in panel (B). Colored circles denote metastable states, and the line of black arrows indicates the optimal path between (ml⁢o⁢w,ml⁢o⁢w) and (ml⁢o⁢w,mh⁢i⁢g⁢h) states. (D) Schematic view of the free energy along the mR axes. The arrows denote the energy barriers Δℱ associated with the various transitions. The dark green arrow denotes ΔF((mhigh,mlow)→(mlow,mlow)); the purple arrow denotes ΔF((mlow,mlow)→(mhigh,mlow)). (E) Values of the free-energy barriers as a function of temperature. Error bars are standard error of the mean (32 recordings, n = 13 fish at 5 different water temperatures). (F) Persistence time of the mean-field anterior rhombencephalic turning region (ARTR) model for all fish and runs at different experimental temperatures. Each dot refers to one fish at one temperature; colors encode temperature.