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Fig. 1
An outbreak in North Carolina with high rates of extrapulmonary and bone disease
(A) Characterization of all secondary cases of the NCG outbreak strain. All patients were HIV negative and had no known immunodeficiencies.
(B) Schematic depicting index and secondary cases in the NCG outbreak.
(C) Destructive lesion of T-spine vertebra 9 with extensive paraspinous abscess (red arrow) caused by Mtb NCG infection.
(D) Lytic lesion of the sternum (red arrow) caused by Mtb NCG infection.
(E) CT scan of paraspinous abscess caused by Mtb NCG infection.
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Reprinted from Cell, 185(24), Saelens, J.W., Sweeney, M.I., Viswanathan, G., Xet-Mull, A.M., Jurcic Smith, K.L., Sisk, D.M., Hu, D.D., Cronin, R.M., Hughes, E.J., Brewer, W.J., Coers, J., Champion, M.M., Champion, P.A., Lowe, C.B., Smith, C.M., Lee, S., Stout, J.E., Tobin, D.M., An ancestral mycobacterial effector promotes dissemination of infection, 4507-4525.e18, Copyright (2022) with permission from Elsevier. Full text @ Cell